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Unlocking the Differences Between the Types of Neurotoxins for the Face

January 15, 2025 | 5 min read
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    Neurotoxin treatments have become a cornerstone of aesthetic medicine, offering a non-invasive way to achieve smoother, younger-looking skin. But with so many options available—Botox, Dysport, Daxxify, and Xeomin—it’s natural to wonder which brand is right for you. If you’re asking yourself “what are neurotoxins” and how do they work in these treatments, understanding the differences between these treatments can help you make an informed decision tailored to your goals.

    What is Botox?

    Botox, short for botulinum toxin type A, is one of the most widely recognized neurotoxins. It works by temporarily blocking nerve signals to specific muscles, reducing their activity and minimizing the appearance of fine lines and wrinkles. FDA-approved in 2002, Botox is effective for treating forehead lines, crow’s feet, frown lines, and other dynamic wrinkles caused by repetitive facial movements. If you’re curious about common Botox areas for treatment, these include not only the forehead and eyes but also other regions where dynamic wrinkles appear. Providers determine the appropriate botox units per area based on individual treatment goals.

    Beyond aesthetics, Botox is also used to address medical conditions such as migraines, excessive sweating, and muscle spasms. Its track record of safety and efficacy has made it a go-to choice for both providers and patients looking for wrinkle relaxers.

    What is Dysport?

    Dysport is another botulinum toxin type A product, often compared to Botox due to its similar mechanism of action. FDA-approved in 2009, Dysport is primarily used to treat moderate to severe frown lines (glabellar lines) between the eyebrows.

    A key differentiator of Dysport is its ability to diffuse over a larger area, making it particularly effective for treating broader regions of the face. Many patients also report a quicker onset of results, often seeing changes within 2-3 days compared to the 5-7 days typical of Botox.

    What is Daxxify?

    Daxxify is the newest entrant in the world of neurotoxins, gaining FDA approval in 2022. Like Botox and Dysport, Daxxify is a botulinum toxin type A treatment for wrinkles and fine lines. However, its standout feature is its longevity—results can last up to six months or longer, nearly twice as long as other neurotoxins.

    This extended duration is attributed to Daxxify’s peptide-enhanced formulation, designed to improve the stability of the toxin. For patients seeking fewer treatments per year, Daxxify may be an ideal choice.

    What is Xeomin?

    Xeomin, approved by the FDA in 2011, is often referred to as the “naked” neurotoxin. Unlike Botox and Dysport, Xeomin contains no accessory proteins, which some argue makes it less likely to cause resistance or allergic reactions over time.

    Primarily used to treat frown lines, Xeomin provides results comparable to Botox, making it a strong contender for patients seeking a simpler formulation. Its clean composition may appeal to those with sensitivities or concerns about long-term use.

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    Comparing Botox, Dysport, Daxxify, and Xeomin

    Composition and Formulation

    • Botox and Dysport contain accessory proteins that help stabilize the neurotoxin but may increase the risk of resistance.
    • Daxxify uses a peptide-enhanced formula, which contributes to its extended duration.
    • Xeomin eliminates accessory proteins, offering a purer alternative.

    Onset of Results

    • Botox: Results typically appear within 5-7 days.
    • Dysport: Often delivers noticeable results within 2-3 days.
    • Daxxify: Takes about 7 days for full results to manifest.
    • Xeomin: Results may take 5-7 days, similar to Botox.

    Duration of Effects

    • Botox and Dysport: Last approximately 3-4 months.
    • Daxxify: Provides results lasting up to 6 months..
    • Xeomin: Effects are comparable to Botox, lasting about 3-4 months.

    Diffusion and Spread

    • Dysport: Known for greater diffusion, which is beneficial for larger treatment areas.
    • Botox, Daxxify, and Xeomin: Offer more localized effects, ideal for precision treatments.

    Dosage and Units

    • Dysport often requires more units than Botox due to differences in formulation, but unit-to-unit pricing balances the cost.
    • Daxxify and Xeomin are dosed similarly to Botox, making them easier to compare directly.

    Effectiveness and Results

    Clinical Studies and Findings

    Clinical trials consistently demonstrate the efficacy of Botox, Dysport, Daxxify, and Xeomin in reducing wrinkles. For example:

    • Daxxify outperforms others in terms of duration, with studies showing effects lasting 24-26 weeks.
    • Botox and Dysport remain reliable choices with high success rates.
    • Xeomin’s clean formulation has been praised for reducing risks of immune resistance.

    How to Tell If It’s Time for a Touch-Up

    Knowing when to schedule your next treatment is key to maintaining optimal results. Look for:

    • Returning Muscle Movement: Subtle muscle activity, like raising your eyebrows, may indicate fading effects.
    • Dynamic Wrinkles Reappearing: Wrinkles become more noticeable during facial expressions.
    • Consult with Your Provider: Regular check-ins can help you stay on track with a personalized treatment plan.

    Side Effects and Safety

    Common Side Effects

    All four neurotoxins share similar side effects, including:

    • Redness or swelling at the injection site
    • Temporary bruising
    • Mild headache or flu-like symptoms

    Minimizing Side Effects

    To reduce risks:

    • Choose a highly experienced provider.
    • Follow pre- and post-treatment care instructions, such as avoiding strenuous exercise or alcohol immediately after the procedure.

    How to Prepare for Your First Neurotoxin Appointment

    Get the most out of your treatment by preparing in advance:

    • Avoid Blood Thinners: Refrain from taking aspirin, ibuprofen, or supplements like fish oil a few days prior to minimize bruising.
    • Stay Hydrated: Hydration can help with post-treatment healing and overall skin health.
    • Clean Skin: Arrive with a clean, makeup-free face to ensure optimal results.

    Cost Comparison

    Price per Unit

    • Botox and Xeomin: Typically range from $10-$15 per unit.
    • Dysport: Slightly lower per-unit cost but requires more units per treatment.
    • Daxxify: Higher price per unit due to its extended duration.

    Overall Treatment Costs

    While Daxxify costs more upfront, its longevity may reduce the need for frequent treatments, balancing the long-term expense. Botox, Dysport, and Xeomin are similarly priced for a typical treatment session.

    Insurance Coverage and Payment Options

    Neurotoxin treatments for cosmetic purposes are generally not covered by insurance. At Elase, we offer competitive pricing options through our exclusive Beauty Bank membership program. This unique approach allows you to save 10-15% or more on every visit, making premium treatments more accessible and affordable. Over time, our Beauty Bank can help you save hundreds of dollars while ensuring you get the best care and results from your aesthetic treatments.

    Choosing the Right Treatment

    Factors to Consider

    When deciding between Botox, Dysport, Daxxify, and Xeomin, consider:

    • Your desired results and treatment frequency
    • Budget and pricing options
    • Treatment areas and goals

    Customizing Neurotoxin Treatments for Different Age Groups

    • In Your 20s and 30s: Focus on preventative treatments to delay the onset of fine lines and wrinkles. Neurotoxins can help relax facial muscles before lines become deeply etched.
    • In Your 40s and Beyond: Target dynamic wrinkles and maintain smoother skin with regular treatments. Combination therapies with dermal fillers may also enhance results for more pronounced signs of aging.

    Consultation with an Elase Provider

    The best way to choose the right treatment is through a consultation with an experienced Elase provider. They will evaluate your skin, discuss your goals, and recommend the most suitable option for your needs.

    Conclusion

    Botox, Dysport, Daxxify, and Xeomin each have distinct benefits, from quick results to extended durations. By understanding their differences and consulting with a knowledgeable provider, you can select the treatment that aligns with your aesthetic goals and lifestyle. Ready to start your journey to smoother, youthful skin? Schedule a consultation with Elase today!

    Reviewed by:

    Kylene May
    Medical Aesthetician Read Bio

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